Fetal bovine serum (FBS) is a commonly used additive in in vitro cell culture because it contains rich growth factors, nutrients and hormones, which are essential for cell growth and division. The following are several main reasons why FBS is often used in cell culture:
1. Nutrition supply
Fetal bovine serum contains a large amount of nutrients such as amino acids, lipids, carbohydrates and vitamins, which are necessary to support normal cell growth and survival.
2. Growth factors and hormones
Fetal bovine serum provides a variety of growth factors and hormones, such as insulin, transforming growth factor (TGF) and epidermal growth factor (EGF), which can effectively stimulate cell proliferation and division.
3. Attachment and growth promoting factors
The fibronectin contained in fetal bovine serum can help cells attach to the surface of plastic culture dishes, which is especially important for cells that need to attach and grow (adherent cells).
4. Maintaining the buffer system
Fetal bovine serum helps maintain the acid-base balance of the cell culture medium, thereby maintaining a stable pH value and providing a stable growth environment for cells.
However, fetal bovine serum also has some disadvantages. For example, its complex composition and differences between batches may affect the reproducibility and consistency of experimental results. In addition, fetal bovine serum may contain unknown biological factors that may have unpredictable effects on cells. Therefore, although fetal bovine serum is still widely used in many cell culture applications, scientists are also exploring serum-free or defined culture media to replace or reduce dependence on fetal bovine serum.
Genom Bio-23-year-old brand, cell culture is more assured
Why choose Genom Bio's FBS?
Source guarantee: Our FBS comes from a high-standard breeding environment, ensuring the high quality of the product.
Strict testing: Each batch of FBS undergoes strict quality control, including sterile filtration and comprehensive biochemical analysis.
Batch consistency: Ensure consistent performance between different batches, bringing you stable experimental results.
Why choose Genom Bio's culture medium?
Formula optimization: Our culture medium is designed for various cell types and can meet the growth needs of different cells.
Strong compatibility: Perfect match with our FBS to ensure healthy cell growth and efficient experimental results.
Wide range of applications: Applicable to basic research, drug screening, vaccine development and other fields.
